These two guys nail it!

Are lipid-lowering guidelines evidence-based?
Lancet: Vol 369 January 20, 2007
J Abramson and JM Wright

They nail what we know, what we don't know and what we need to know.

Here's more from one of them

Complicating the statin issue even more for women, the five studies of statins that examined the risk of breast cancer found a 33 percent higher rate in women taking statins than in those taking placebos. There were not enough women in these studies to make this increase statistically significant, but clearly more research is needed here. In fact, a large clinical trial based at the University of California, San Diego, is now quantifying the extent to which statin users experience a variety of adverse effects.

Here he is being interviewed
You'll need quicktime for this. Fast forward past the Tony Blair bit. A statin promoter is on first.