Statins - secondary prevention
These 4 trials reconfirm the benefit of statins for patients with elevated cholesterol and coronary disease and expand the benefit to patients with clinically evident occlusive coronary, cerebral or peripheral vascular disease and a total cholesterol >3.5 mM. Despite the lack of reporting of total SAEs in these trials, one measure of overall health benefit, total mortality, was reduced, pooled RR 0.84 [0.79–0.88], ARR 2.1%, NNT 48 for 3 to 5 years.
48 people have to be treated for 3 to 5 years to prevent one death.
No comments:
Post a Comment