Lipex with other drugs

Interactions

With simvastatin and lovastatin, risk of muscle toxicity increases when taken with other drugs, especially ones also broken down by enzymes CYP34A: clarithromycin, cyclosporine, erythromycin, clarithromycin, fibrates, itraconazole, ketoconazole, niacin over 1 gram per day, protease inhibitors, ritonavir, Nefazodone

Avoid doses of lovastatin higher than 40 milligrams per day or simvastatin higher than 20 milligrams per day when also using: amiodarone, verapamil. ? adjust dose of digoxin and warfarin. Dilantin and other anticonvulsants may reduce effects of simvastin.