Grapefruit Juice

The article recommends avoiding grapefruit juice or grapefruit if you are using any of the following drugs because they require careful control of blood concentrations: amiodarone (CORDARONE, and other generic versions), carbamazepine (TEGRETOL): and others), cyclosporine (SANDIMMUNE and others), sirolimus (RAPAMUNE) or tacrolimus (PROGRAF). Other citrus fruits, including pomelos and Seville oranges, which also contain the chemicals inhibiting drug metabolism, should also be avoided if using the above drugs.

The Medical Letter advises that if you are using any of the other drugs listed in the article, “limiting daily intake to one 8-oz glass of juice or one half of a fresh grapefruit would probably avoid any adverse drug interactions.”